FIGURE

Figure 4

ID

ZDB-FIG-210902-111

Publication

Feng et al., 2021 - FDA-Approved Drug Screening for Compounds That Facilitate Hematopoietic Stem and Progenitor Cells (HSPCs) Expansion in Zebrafish

Other Figures

All Figure Page

Back to All Figure Page

Figure 4

Ergocalciferol and panthenol facilitate HSPCs expansion in a dosage-dependent manner. (A) Schematic diagram of concentration gradient using ergocalciferol and panthenol. (B) WISH of cmyb with different concentration (5, 10, 20 ?M). Blue arrowheads indicate cmyb⁺ signals. (C) WISH of lyz (upper) and gata1 (bottom) after treating with ergocalciferol and panthenol using 20 ?M. (D,E) Quantification of lyz⁺ (left) and gata1⁺ (right) signals areas in the CHT region. (Pixels, lyz⁺ signals; DMSO, 4980 � 467; Ergocalciferol, 8678 � 617; Panthenol, 7524 � 468; gata1⁺ signals; DMSO, 8525 � 768; Ergocalciferol, 16,350 � 1816; Panthenol, 13,790 � 1252). Scale bar, 50 ?m; Mean � SEM, n = 8; ** p < 0.01, *** p <0.001.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cells