Figure 7
- ID
- ZDB-FIG-210801-61
- Publication
- Gawel et al., 2021 - 6-Gingerol, a Major Constituent of Zingiber officinale Rhizoma, Exerts Anticonvulsant Activity in the Pentylenetetrazole-Induced Seizure Model in Larval Zebrafish
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The effect of 6-GIN on (A) gabra1a, (B) grin1a, (C) grin2b, (D) gria1a, (E) gria2a, and (F) gria3b mRNA expression in PTZ-treated zebrafish larvae. After a 24 h incubation in 6-GIN (37.5 µM), zebrafish larvae were exposed to PTZ (20 mM) for 90 min. Next, zebrafish larvae were collected in a pool of n = 10/sample. mRNA levels were normalized against gapdh. Data were analyzed using one-way ANOVA with Tukey’s post hoc test. Data are depicted as a mean ± SEM (n = 3/group). *** p < 0.01, ** p < 0.01, * p < 0.05 vs. Veh + veh; && p < 0.01 vs. Veh + PTZ. 6-GIN—6-gingerol, PTZ—pentylenetetrazole, Veh—vehicle. n—refers to the total number of samples. |