FIGURE

Figure 5

ID

ZDB-FIG-210801-59

Publication

Gawel et al., 2021 - 6-Gingerol, a Major Constituent of Zingiber officinale Rhizoma, Exerts Anticonvulsant Activity in the Pentylenetetrazole-Induced Seizure Model in Larval Zebrafish

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Figure 5

LFP events detected from the optic tectum of 7-day-old zebrafish larvae pre-exposed for 24 h to 6-GIN (37.5 µM). Subsequently, each larva was incubated with 20 mM PTZ or Veh for 5 min, before being mounted in agarose for LFP recordings. Data are shown as: (A) the number of events (nr/20 min), and (B) the mean duration of events (s/20 min). Data were analyzed using one-way ANOVA followed by Tukey’s post hoc test. Data are depicted as mean ± SEM. Veh + veh (n = 8), 6-GIN 37.5 + Veh (n = 6), Veh + PTZ (n = 14), 6-GIN 37.5 + PTZ (n = 16). *** p < 0.001 vs. Veh + veh; &&& p < 0.001 vs. Veh + PTZ. (C) Representative traces of recordings. 6-GIN—6-gingerol, PTZ—pentylenetetrazole, Veh—vehicle. n—refers to the total number of larvae.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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