FIGURE

FIG 6

ID

ZDB-FIG-210726-15

Publication

Horton et al., 2021 - Candida auris Cell Wall Mannosylation Contributes to Neutrophil Evasion through Pathways Divergent from Candida albicans and Candida glabrata

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FIG 6

C. aurispmr1Δ and van1Δ strains grow to lower burdens in the larval zebrafish hindbrain in the presence of neutrophils. Wild-type (A) or transgenic zebrafish expressing a dominant Rac2^D57N mutation in neutrophils (B) were inoculated with C. auris by hindbrain injection. Fungal burden was quantified at 0, 1, 3, and/or 5 days postinfection by homogenizing whole larvae and plating for CFU. n = 20 to 24; experiments were performed in three replicates; mean with SEM are shown; *, P < 0.05; ns, not significant by Brown-Forsythe and Welch ANOVA with Dunnett’s T3 multiple comparisons to C. auris WT.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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