FIGURE

FIGURE 7

ID

ZDB-FIG-210718-27

Publication

?ysyganicz et al., 2021 - Loss of Deacetylation Enzymes Hdac6 and Sirt2 Promotes Acetylation of Cytoplasmic Tubulin, but Suppresses Axonemal Acetylation in Zebrafish Cilia

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FIGURE 7

Change in mutant behavior. (A) Tracks of swimming patterns of Wild type and Triple mutant fish treated and untreated with disorientating stimulus. Black lines correspond to slow swimming (<5 mm/s), green lines indicate medium speed (5–10 mm/s) and red lines indicate fast swimming (>10 mm/s). The figure shows a representative swimming pattern of one larvae. (B) Swimming distance normalized to swimming distance by non-treated wild types. (C) TAP952 stained cilia in cristae of treated and untreated fish. (D) Number of cilia in cristae (mean with 95% CI. T-test *p < 0.05). ns, no significant.

Expression Data

Antibody:	Ab2-tub-glyc
Fish:	WT hdac10^sh401/sh401; hdac6^sh400/sh400; sirt2^sh626/sh626
Condition:	mechanical stress
Anatomical Terms:	anterior crista kinocilium lateral crista kinocilium posterior crista kinocilium
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT hdac10^sh401/sh401; hdac6^sh400/sh400; sirt2^sh626/sh626
Condition:	mechanical stress
Observed In:	anterior crista kinocilium lateral crista kinocilium posterior crista kinocilium whole organism swimming behavior
Stage:	Day 5

Phenotype Detail

Acknowledgments

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