FIGURE

FIGURE 2

ID

ZDB-FIG-210327-81

Publication

Chung et al., 2021 - Development of the CK-MB-1 trastuzumab-resistant HER2-positive breast cancer cell line and xenograft animal models

Other Figures

All Figure Page

Back to All Figure Page

FIGURE 2

Characteristics of the CK‐MB‐1 cell line. (A) Western blotting confirmed HER2 positivity, ER/PR negativity, and no expression of EGFR in CK‐MB‐1 cells. (B) There was no loss of PTEN protein expression in CK‐MB‐1 cells. (C) HER2 gene amplification was detected by FISH. Orange signals were HER2 genes and green signals were chromosome 17 centromeres. (D) Sanger sequencing of CK‐MB‐1 cells did not reveal common PIK3CA mutation in exons 9 and 20. EGFR, epidermal growth factor receptor; ER, estrogen receptor; HER2, human epidermal growth factor receptor 2; PIK3CA, phosphoinositide‐3‐kinase, catalytic, alpha; PR, progesterone receptor; PTEN, phosphatase and tensin homolog

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cancer Med