FIGURE

FIGURE 2

ID

ZDB-FIG-210324-10

Publication

Liu et al., 2021 - ITPR1 Mutation Contributes to Hemifacial Microsomia Spectrum

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FIGURE 2

Expression pattern of ITPR1. (A) At E 11.5, ITPR1 is expressed in the frontonasal process, first branchial arch, and second branchial arch, like the mandibular process, nasal pit, otocyst, trigeminal (V) ganglia, and facial-acoustic (VII-VIII) ganglia. (B) By E13.5, ITPR1 shows significant expression at the craniofacial region, like the tooth bud, mandibular mesenchyme, (C) epithelial layer of palate shelves, and (D) Meckel’s cartilage. ITPR1 is marked in green fluorescence. DNA was stained by DAPI and is marked in blue fluorescence. Abbreviations are as follows: f.p, frontonasal process; f.n, nasal pit; m.p, mandibular process; o, otocyst; t.g, trigeminal (V) ganglia; f.g, facioacoustic (VII-VIII) ganglia; p, palate, t, tongue; t.b, tooth bud; m.c, Meckel’s cartilage; m.d, mandible.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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