FIGURE

Fig. 1

ID

ZDB-FIG-210301-156

Publication

Ferrero et al., 2020 - A csf1rb mutation uncouples two waves of microglia development in zebrafish

Other Figures

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Fig. 1

Csf1ra and csf1rb paralogs have non-overlapping distribution during early development, except for microglia. (A-O) WISH expression profiles of csf1ra (A-E) and csf1rb (F-J) in wild-type, and csf1rb in runx1^−/− (K-O) embryos, at the indicated stages. All lateral views, except for E, J and O, shown in dorsal view. Black arrowheads indicate cells in each region. Red arrowheads indicate microglia. Insets show magnification of boxed areas. THY, thymus. Scale bars: 200 µm (30 and 36 hpf); 180 µm (48 hpf); 150 µm (72 hpf).

Expression Data

Genes:	csf1ra csf1rb
Fish:	WT runx1^hg1/hg1
Anatomical Terms:	brain microglial cell caudal hematopoietic tissue dorsal aorta otic vesicle retina microglial cell thymus thymus primordium (all 7)
Stage Range:	Prim-15 to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	runx1^hg1/hg1
Observed In:	caudal hematopoietic tissue dorsal aorta otic vesicle thymus thymus primordium
Stage Range:	Prim-25 to Protruding-mouth

Phenotype Detail

Acknowledgments

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