FIGURE

Fig. 3

ID

ZDB-FIG-210204-17

Publication

Schild et al., 2020 - Hif-1alpha stabilisation is protective against infection in zebrafish comorbid models

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Fig. 3

Mm retains neutrophils at the somite infection site at the expense of migration to the tailfin wound. (A) Schematic of experiment for B?D, showing PC of neutrophils in the CHT of mpx:Kaede embryos. (B) Example fate?tracks of red neutrophils that were photoconverted in the CHT and migrated to either PVP or Mm infection in the somite over 4 hpi/w. Data shown are examples from two independent experiments with 10 fish per group. Scale bar = 100 ?m. (C) Stereo?fluorescence micrographs of the location of red photoconverted neutrophils that originated in the CHT in PVP and Mm?infected larvae. Data shown are examples from two independent experiments with 10 fish per group. Scale bar = 100 ?m. (D) Heatmap of location of red photoconverted neutrophils that originated in the CHT over time. Data shown are n = 5 embryos per group accumulated from two independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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