FIGURE
Fig. 6
- ID
- ZDB-FIG-201202-12
- Publication
- Loontiens et al., 2020 - PHF6 Expression Levels Impact Human Hematopoietic Stem Cell Differentiation
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Fig. 6
Loss of PHF6 mimics reduced Notch activity during human T cell development. (A–C) (left) Flow cytometry analysis and (right) absolute cell counts of control versus PHF6 shRNA transduced or DMSO versus 1 μM GSI treated CD34+ thymocytes in OP9-DLL1 cocultures showing (A) the development of CD4+CD8β+ DP thymocytes after 18 days of coculture, (B) the development of CD3+TCRαβ+ thymocytes after 25 days of coculture and (C) the development of CD3+TCRγδ+ thymocytes after 25 days of coculture. Data shows the average of 3 independent experiments and errors bars show SEM. *P < 0.05 (paired t-test). |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
Phenotype Detail
Acknowledgments
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Full text @ Front Cell Dev Biol