FIGURE

Figure 3

ID

ZDB-FIG-200724-28

Publication

Lee et al., 2020 - Human ARF Specifically Inhibits Epimorphic Regeneration in the Zebrafish Heart

Other Figures

All Figure Page

Back to All Figure Page

Figure 3

ARF expressed in ARF:ARF fish suppresses cardiomyocyte proliferation. (a) Myocyte enhancer factor 2 (Mef2), proliferating cell nuclear antigen (PCNA), and 4′,6-diamidino-2-phenylindole (DAPI) staining in WT and ARF:ARF fish at 11 dpi. Blue stains are for all nuclei. Red stains are for Mef2, a cardiomyocyte nuclear marker. Green stains are for PCNA, a cell cycling marker. (b) The cardiomyocyte (CM) proliferation index shows decreased cardiomyocyte cycling in ARF:ARF fish. The CM proliferation index was calculated by counting Mef2⁺/PCNA⁺ cells out of total Mef2⁺ cells in the injury zone. N = 8 hearts. Results are shown as mean ± standard error. The * represents a statistically significant difference.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	zf707Tg (AB)
Condition:	cold damage: heart
Observed In:	cardiac muscle cell proliferation
Stage:	Adult

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Genes (Basel)