FIGURE

FIGURE 3

ID

ZDB-FIG-200613-9

Publication

R�ltgen et al., 2020 - Buruli ulcer: The Efficacy of Innate Immune Defense May Be a Key Determinant for the Outcome of Infection With Mycobacterium ulcerans

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FIGURE 3

Early host immune response to M. ulcerans infection illustrated in histological sections of a nodular lesion 6 weeks after subcutaneous infection of pigs (A–D) (from Bolz et al., 2016b) and in a sketch depicting the cellular composition of the lesion (E) (created with biorender.com). Histopathological analysis of pig lesions shows a central necrotic core containing extracellular M. ulcerans bacilli (A1,A2; AFB stained with Ziehl–Neelsen staining) and neutrophilic debris (B1,B2). The necrotic core is surrounded by layers of neutrophils (B1,B2) and macrophages (C1,C2), heavily interspersed with T-cells (D1,D2).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Microbiol