FIGURE

FIGURE 2

ID

ZDB-FIG-200613-8

Publication

R�ltgen et al., 2020 - Buruli ulcer: The Efficacy of Innate Immune Defense May Be a Key Determinant for the Outcome of Infection With Mycobacterium ulcerans

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FIGURE 2

Structure and cellular composition of granulomas. Early innate M. marinum granulomas, as described in zebrafish embryos, are composed of compact, organized aggregates of macrophages that have either transformed into epithelioid cells with tightly interdigitated cell membranes or have fused to become multinucleated giant cells. Bacilli are found both extracellularly in the necrotic core of the granuloma and intracellularly within phagocytes (A). The characteristic mature tuberculous granuloma is populated by many other cell types such as neutrophils, dendritic cells, B and T cells, natural killer cells, and foam cells, which are macrophages with accumulated lipids (B) (created with biorender.com).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front Microbiol