Figure 4
- ID
- ZDB-FIG-200530-43
- Publication
- Ye et al., 2020 - Yap-lin28a axis targets let7-Wnt pathway to restore progenitors for initiating regeneration
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(A?D) ET4;ET20;hs:lin28a larvae were incorporated with BrdU for 24 hr following heat-shock and/or neomycin treatment. (A, B) Overexpression of lin28a increased number of proliferative SCs (SC+) in both untreated and neomycin conditions. (C, D) BrdU plots and rose diagrams indicate that locations of SC+ still remain dorsally and ventrally polarized in hs:lin28a. (E, F) OverexpressUion of lin28a is sufficient to partially restore the exhausted sox2+ progenitors post LY. Scale bar equals 10 ?m. |
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| Stage: | Day 5 |