FIGURE

Figure 5

ID
ZDB-FIG-200406-28
Publication
Schmid et al., 2020 - Mechanotransduction Activity Facilitates Hair Cell Toxicity Caused by the Heavy Metal Cadmium
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Figure 5

Copper fails to protect against cadmium-induced hair cell death. (A) At doses of 0.5 μM and higher copper sulfate caused significant hair cell death on its own. ****p < 0.0001 by Two-Way ANOVA and Šídák multiple comparisons test as compared to the 0-copper sulfate control. Using copper sulfate in concentrations up to 1 μM failed to protect against hair cell death in response to 30 μM of cadmium chloride. (B) The 0.25 μM dose of copper sulfate failed to show a significant reduction in hair cell death at all cadmium chloride doses tested. Data are displayed as mean ± standard deviation. n = 10 fish for all groups. (C) Representative images of the O2 Neuromast in control (top) and copper sulfate treated (bottom) fish following treatment with either 0 (left) or 60 (right) μM cadmium chloride.

Expression Data

Expression Detail
Antibody Labeling
Phenotype Data

Phenotype Detail
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.