FIGURE

Figure 4

ID

ZDB-FIG-200406-27

Publication

Schmid et al., 2020 - Mechanotransduction Activity Facilitates Hair Cell Toxicity Caused by the Heavy Metal Cadmium

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Figure 4

Zinc shows limited protection against cadmium-induced hair cell death. Zinc sulfate failed to reduce hair cell death when administered (A) alongside cadmium chloride and only showed a slight reduction at the highest dose tested when administered (B) 1 h before and during cadmium chloride treatment. This protection was not seen when tested against a range of cadmium chloride doses (C). Data are displayed as mean ± standard deviation. ***p < 0.001 as compared to the 0 zinc sulfate control by Two-Way ANOVA and Šídák multiple comparisons test. n = 10 fish for all groups. (D) Representative images of the IO4 Neuromast in control (top) and zinc sulfate treated (bottom) fish following treatment with either 0 (left) or 60 (right) μM cadmium chloride.

Expression Data

Antibody:	Ab6-pvalb
Fish:	AB
Condition:	chemical treatment by environment: cadmium dichloride
Anatomical Term:	neuromast hair cell
Stage:	Day 5

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	AB
Condition:	chemical treatment by environment: cadmium dichloride
Observed In:	neuromast hair cell
Stage:	Day 5

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Front. Cell. Neurosci.