Copper fails to protect against cadmium-induced hair cell death. (A) At doses of 0.5 μM and higher copper sulfate caused significant hair cell death on its own. ****p < 0.0001 by Two-Way ANOVA and Šídák multiple comparisons test as compared to the 0-copper sulfate control. Using copper sulfate in concentrations up to 1 μM failed to protect against hair cell death in response to 30 μM of cadmium chloride. (B) The 0.25 μM dose of copper sulfate failed to show a significant reduction in hair cell death at all cadmium chloride doses tested. Data are displayed as mean ± standard deviation. n = 10 fish for all groups. (C) Representative images of the O2 Neuromast in control (top) and copper sulfate treated (bottom) fish following treatment with either 0 (left) or 60 (right) μM cadmium chloride.
Acknowledgments
This image is the copyrighted work of the attributed author or publisher, and
ZFIN has permission only to display this image to its users.
Additional permissions should be obtained from the applicable author or publisher of the image.
Full text @ Front. Cell. Neurosci.
Your Input Welcome
Thank you for submitting comments. Your input has been emailed to ZFIN curators who may contact you if
additional information is required.
Oops. Something went wrong. Please try again later.