FIGURE

Fig. 7

ID

ZDB-FIG-200325-6

Publication

Wang et al., 2019 - The Application of Methylprednisolone Nanoscale Zirconium-Porphyrin Metal-Organic Framework (MPS-NPMOF) in the Treatment of Photoreceptor Degeneration

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Fig. 7

Cell proliferation of light-lesioned retina following injection of MPS-NPMOF. (A) PCNA staining in sections taken from retinas at 1, 2, 3 and 4 dpl. (B) Statistical analysis of the percentage of PCNA-positive cells from GCL to ONL. There was a significantly higher percentage in the MPS-NPMOF group than in the PBS and MPS groups at 3 dpl (ANOVA, *p<0.05). (C and D) The expression of ascl1a and sox2 mRNA. Note that ascl1a was increased in the MPS-NPMOF group at 36, 48 and 72 hpl, while sox2 was increased at 48 and 72 hpl (ANOVA, *p<0.05). Scale bar in (A): 20 μm. Abbreviations: ONL, outer nuclear layer; INL, inner nuclear layer; GCL, ganglion cell layer.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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