FIGURE

Fig. 17

ID

ZDB-FIG-190801-13

Publication

Nowak-Sliwinska et al., 2018 - Consensus guidelines for the use and interpretation of angiogenesis assays

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Fig. 17

Identification of tip cells. The tip cell is the leading cell of an angiogenic sprout with long filopodia extensions, followed by stalk cells that proliferate and phalanx cells that form a matured new capillary. a Tip cells in the developing mouse retina can be identified by staining with isolectin B4 (IB4). b The mouse retinal vasculature (IB4) follows the astrocytic meshwork (GFAP) when forming the superficial vascular plexus during development. c A combination of collagen type IV IHC (in pink) for general staining of blood vessels and ISH for PDGFB (black) for specific identification of tip cells in the developing mouse retina. d Tip cells in endothelial cell cultures are identified by CD34

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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