FIGURE

Fig. 3

ID

ZDB-FIG-181130-26

Publication

Castillo-Robles et al., 2018 - smarce1 mutants have a defective endocardium and an increased expression of cardiac transcription factors in zebrafish

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Fig. 3

Rescue of the heart looping by smarce1 mRNA injection in smarce1 mutant embryos. Whole-mount in situ hybridization detects transcripts for the cardiomyocyte marker cmlc2. A-B. Embryos at 48 hpf showing a normal heart (A) and a smarce1^−/− heart with a defective looping (B). (C–H) Analysis of heart looping at 72 hpf. Buffer injected embryos present a normal heart in control siblings (C) and a non-looped heart in all the mutants (D). (E–H) smarce1 mRNA injected embryos showing the rescue of the heart looping in the mutant embryos. Complete rescue is shown in (F); a partial rescue in (G); and the failing of rescue in (H). Scale bars: 50 μm.

Expression Data

Gene:	myl7
Fish:	WT smarce1^una1/una1
Anatomical Terms:	atrial myocardium ventricular myocardium
Stage Range:	Long-pec to Protruding-mouth

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	smarce1^una1/una1
Observed In:	heart heart looping
Stage Range:	Long-pec to Protruding-mouth

Phenotype Detail

Acknowledgments

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