FIGURE

Fig. S9

ID

ZDB-FIG-180913-18

Publication

Yang et al., 2018 - Sensing of cytosolic LPS through caspy2 pyrin domain mediates noncanonical inflammasome activation in zebrafish

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Fig. S9

Representation of the zebrafish larvae immersion Infection Model.

(a) The zebrafish microinjection and immersion infection procedures. (b) Generation of caspy2 morphant zebrafish by morpholino oligonucleotide (MO)-mediated knockdown. The upper diagram shows the region of caspy2 targeted to block translation. (c and d) Analysis of the phenotypes of caspy2-MO- and control-MO-injected larvae. (c) Immunoblotting of caspy2 expression in morphants and controls up to 5 days post fertilization (dpf). (d) Representative images of the phenotypes of caspy2-MO- and control-MO-injected zebrafish up to 120 h post fertilization (hpf). (c and d) Results are representative of at least three independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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