FIGURE

Fig. 2

ID

ZDB-FIG-180807-10

Publication

Lai et al., 2018 - Liver-directed microRNA-7a depletion induces nonalcoholic fatty liver disease by stabilizing YY1-mediated lipogenic pathways in zebrafish

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Fig. 2

Generation of miR-7a-sponge transgenic zebrafish. (A) Cloning of pri-miR-7a and miR7a-SP into LF2.8 expression vectors. Stem-loop structure of premiR-7a, in which mature miR-7a is highlighted in red. (B) Red fluorescent images of C7aSP expression in the entire body of bC7aSP (1, 9 pdf, magnification 40×, scale bars: 200 μm; 2, 4 mpf, magnification 40×, scale bars: 100 mm) and the livers of hC7aSP1 (3, 9 pdf, magnification 40×, scale bars: 200 μm; 4, 4 mpf, magnification 40×, scale bars: 100 mm). (C) Stem-loop RT-qPCR analysis of mature miR-7a of the liver, brain, intestine, and muscle tissues from the three transgenic lines, bC7aSP and hC7aSP1 and 2. **

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Biochim. Biophys. Acta