FIGURE

Fig. S4

ID

ZDB-FIG-180711-70

Publication

Kontarakis et al., 2018 - Mir-126 is a conserved modulator of lymphatic development

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Fig. S4

mir-126 mutants do not exhibit an obvious angiogenic phenotype. (A) Brightfield micrograph of 48 hpf wild-type sibling and mir-126^-/- embryos in. lateral view. B) Confocal micrographs of 48 hpf TgBAC(etv2: EGFP) wild-type sibling and mir-126^-/- embryos in lateral views; arrows point to ISVs in the trunk. (C) Brightfield micrographs of 48 hpf wild-type sibling and mir-126^-/- embryos in dorsal views. D) Confocal micrographs of 48 hpf TgBAC(etv2: EGFP) wild-type sibling and mir-126^-/- embryos in dorsal views; arrows point to PHBCs (primordial hindbrain channels). BA (basal artery), CtAs (central arteries).

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	mir126a^bns2/bns2; mir126b^bns3/bns3; ci1Tg
Observed In:	intersegmental vessel primordial hindbrain channel sprouting angiogenesis
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 437(2), Kontarakis, Z., Rossi, A., Ramas, S., Dellinger, M.T., Stainier, D.Y.R., Mir-126 is a conserved modulator of lymphatic development, 120-130, Copyright (2018) with permission from Elsevier. Full text @ Dev. Biol.