FIGURE

Fig. S3

ID

ZDB-FIG-180622-36

Publication

Missinato et al., 2018 - Dusp6 attenuates Ras/MAPK signaling to limit zebrafish heart regeneration

Other Figures

All Figure Page

Back to All Figure Page

Fig. S3

dusp6 mutant hearts have increased pERK (A) Cryosections of uninjured Tg(fli1a:EGFP)^y1 zebrafish hearts immunostained for pERK. dusp6 heart (n=9) have increased pERK staining than WT hearts (n=10). Images are from one representative hearts for each group. Non-consecutive sections (S) are shown. S-2 is an initial section, in proximity of the compact myocardium. S-12 is the central section of the heart. (B) Quantification of pERK in WT and dusp6 mutant hearts at 5 months of age. pERK staining was calculated as sum of pERK⁺ immunostained area divided by the compact myocardium area, and expressed as percentage. ***p<0.001. Student’s t-test. Scale bars, 100 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Development