FIGURE

Fig. 2

ID

ZDB-FIG-180413-19

Publication

Gamba et al., 2017 - Collagenolytic Activity Is Associated with Scar Resolution in Zebrafish Hearts after Cryoinjury

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Fig. 2

MMPs transcripts increase in zebrafish ventricles after cryoinjury. (A) RT-quantitative PCR for mmp2, mmp9, mmp13a, mmp14a, and mmp14b in ventricles at several time points after cryoinjury (six to eight ventricles per time point). Significant difference with uninjured hearts: **** p < 0.0001, ** p < 0.01, * p < 0.05; (B,C) in situ hybridization in uninjured and 14 dpc hearts of mmp2 (n = 1 and 2, respectively) and mmp14a (n = 2 and 2, respectively) transcripts respectively; (B’,C’) Magnification of the boxes in (B,C), respectively; (D,E) AFOG staining on consecutive sections of 14 dpc hearts shown in (B,C) respectively for comparison with the wound area (fibrin in red, collagen in blue, and counterstaining in orange).

Expression Data

Genes:	mmp2 mmp9 mmp13a.1 mmp14a mmp14b
Fish:	WT
Condition:	cold damage: cardiac ventricle
Anatomical Term:	cardiac ventricle
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	cold damage: cardiac ventricle
Observed In:	cardiac ventricle
Stage:	Adult

Phenotype Detail

Acknowledgments

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