FIGURE

Fig. 3

ID

ZDB-FIG-180122-33

Publication

Song et al., 2017 - Coral-Derived Natural Marine Compound GB9 Impairs Vascular Development in Zebrafish

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Fig. 3

Pericardial edema and circulation defect in GB9 treated embryo. (A–C) At 48 hpf, representative edema fish (arrow in (B)) and quantitative results showed 60% of GB9 treated embryo (n = 20) with mild to severe pericardial edema compared to untreated control (n = 19). (D,E) GB9 treatment in transgenic Tg(gata1:dsRed) embryos with dsRed-labeled blood cells showed slow to no circulation at 52 hpf (E) compared to wild-type fish (D). (F) Circulation defects at the ISV/DLAV or slow to lose axial circulation of the aorta/vein in the trunk region are quantified in control (n = 18) and GB9 treated embryo (n = 18) at 52 hpf. The scale bar in (A,B) is 500 μm, and in (D,E) represents 200 μm.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Int. J. Mol. Sci.