Fig. 6
- ID
- ZDB-FIG-180109-14
- Publication
- Turrini et al., 2017 - Optical mapping of neuronal activity during seizures in zebrafish
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High-throughput combined fluorescence and behavioural assay. (a) Maximum intensity projection of a 13?minute segment of the recording. Well content: 1?6 control, 7?12 1?mM PTZ, 13?18 15?mM PTZ, 19?24 1?mM PTZ?+?50 ?M Baclofen, 25?30 15?mM PTZ?+?50 ?M Baclofen, 31?36 15?mM PTZ?+?5 ?M Tetrodotoxin, 37 fish water, 38 fish water?+?2?mM Kynurenate, 39?43 15?mM PTZ?+?2?mM kynurenate, 44?49 15?mM PTZ?+?5?mM Valproate, 50?55 15?mM PTZ (after pre-incubation in 2?mM d-tubocurarine for 10?minutes before starting the measurement), 56?61 15?mM PTZ?+?160?mg/L Tricaine. (b) Average ?F/F0 and (c) swimming velocity for the different conditions tested. Error bars: s.e.m. |