ZFIN ID: ZDB-FIG-171219-3
Konantz et al., 2016 - Evi1 regulates Notch activation to induce zebrafish hematopoietic stem cell emergence. The EMBO journal   35(21):2315-2331 Full text @ EMBO J.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage Range: Prim-15 to Prim-25
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage Range: Prim-15 to Prim-25

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
myb TU control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
kca3Tg; kca4Tg chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
nkuasrfp1aTg; ubs3Tg + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
notch1b TU control Prim-25 ventral wall of dorsal aorta ISH
TU chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta ISH
TU + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta ISH
nkuasrfp1aTg; ubs3Tg + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta ISH
runx1 TU control Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
TU + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
kca3Tg; kca4Tg chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
nkuasrfp1aTg; ubs3Tg + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
TU chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta notch1b expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
TU + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta notch1b expression decreased amount, abnormal
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell myb expression decreased amount, abnormal
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression decreased amount, abnormal
kca3Tg; kca4Tg chemical treatment: wortmannin Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell myb expression amount, ameliorated
Prim-25 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression amount, ameliorated
nkuasrfp1aTg; ubs3Tg + MO5-mecom + MO6-mecom standard conditions Prim-15 ventral wall of dorsal aorta notch1b expression amount, ameliorated
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell myb expression amount, ameliorated
Prim-15 ventral wall of dorsal aorta hematopoietic multipotent progenitor cell runx1 expression amount, ameliorated
Full text @ EMBO J.