ZFIN ID: ZDB-FIG-171019-21
Chen et al., 2017 - E-Prostanoid 3 Receptor Mediates Sprouting Angiogenesis Through Suppression of the Protein Kinase A/β-Catenin/Notch Pathway. Arteriosclerosis, Thrombosis, and Vascular Biology   37(5):856-866 Full text @ Arterio., Thromb., and Vas. Bio.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Condition:
Knockdown Reagents:
Anatomical Terms:
Stage: Prim-5
PHENOTYPE:
Fish:
Condition:
Knockdown Reagents:
Observed In:
Stage: Prim-5

Fig. 3 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
dll4 WT control Prim-5 trunk vasculature ISH
WT chemical treatment: antagonist Prim-5 trunk vasculature ISH
WT + MO1-ptger3 standard conditions Prim-5 trunk vasculature ISH
EGFP y1Tg control Prim-5 dorsal aorta IFL
Prim-5 intersegmental vessel IFL
Prim-5 posterior cardinal vein IFL
Prim-5 trunk vasculature IFL
y1Tg + MO1-dll4 standard conditions Prim-5 dorsal aorta IFL
Prim-5 intersegmental vessel IFL
Prim-5 posterior cardinal vein IFL
Prim-5 trunk vasculature IFL
y1Tg + MO1-dll4 + MO1-ptger3 standard conditions Prim-5 dorsal aorta IFL
Prim-5 intersegmental vessel IFL
Prim-5 posterior cardinal vein IFL
Prim-5 trunk vasculature IFL
y1Tg + MO1-ptger3 standard conditions Prim-5 dorsal aorta IFL
Prim-5 intersegmental vessel IFL
Prim-5 posterior cardinal vein IFL
Prim-5 trunk vasculature IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT chemical treatment: antagonist Prim-5 trunk vasculature dll4 expression increased amount, abnormal
WT + MO1-ptger3 standard conditions Prim-5 trunk vasculature dll4 expression increased amount, abnormal
y1Tg + MO1-dll4 + MO1-ptger3 standard conditions Prim-5 dorsal longitudinal anastomotic vessel morphology, ameliorated
Prim-5 intersegmental vessel morphology, ameliorated
Prim-5 intersegmental vessel sprouting angiogenesis occurrence, ameliorated
y1Tg + MO1-ptger3 standard conditions Prim-5 dorsal longitudinal anastomotic vessel hypoplastic, abnormal
Prim-5 intersegmental vessel hypoplastic, abnormal
Prim-5 intersegmental vessel sprouting angiogenesis decreased occurrence, abnormal
Full text @ Arterio., Thromb., and Vas. Bio.