ZFIN ID: ZDB-FIG-170908-43
Mathews et al., 2016 - Cholesterol Biosynthesis Supports Myelin Gene Expression and Axon Ensheathment through Modulation of P13K/Akt/mTor Signaling. The Journal of neuroscience : the official journal of the Society for Neuroscience   36:7628-39 Full text @ J. Neurosci.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Conditions:
Knockdown Reagents:
Anatomical Terms:
Stage: Day 4
PHENOTYPE:
Fish:
Conditions:
Knockdown Reagents:
Observed In:
Stage: Day 4

Fig. 7 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP co18Tg; co19Tg control Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg chemical treatment by environment: sirolimus Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg chemical treatment by environment: U0126 Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg + MO1-ptena + MO4-tp53 control Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg + MO1-ptena + MO4-tp53 chemical treatment by environment: sirolimus Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg + MO1-ptena + MO4-tp53 chemical treatment by environment: U0126 Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg + MO4-tp53 control Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg + MO4-tp53 chemical treatment by environment: sirolimus Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
co18Tg; co19Tg + MO4-tp53 chemical treatment by environment: U0126 Day 4 oligodendrocyte myelin sheath IFL
Day 4 spinal cord oligodendrocyte IFL
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
co18Tg; co19Tg control Day 4 oligodendrocyte myelin sheath length, normal
co18Tg; co19Tg chemical treatment by environment: sirolimus Day 4 oligodendrocyte myelin sheath decreased length, abnormal
co18Tg; co19Tg chemical treatment by environment: U0126 Day 4 oligodendrocyte myelin sheath length, normal
co18Tg; co19Tg + MO1-ptena + MO4-tp53 control Day 4 oligodendrocyte myelin sheath increased length, abnormal
co18Tg; co19Tg + MO1-ptena + MO4-tp53 chemical treatment by environment: sirolimus Day 4 oligodendrocyte myelin sheath decreased length, ameliorated
co18Tg; co19Tg + MO1-ptena + MO4-tp53 chemical treatment by environment: U0126 Day 4 oligodendrocyte myelin sheath length, ameliorated
co18Tg; co19Tg + MO4-tp53 control Day 4 oligodendrocyte myelin sheath length, normal
co18Tg; co19Tg + MO4-tp53 chemical treatment by environment: sirolimus Day 4 oligodendrocyte myelin sheath decreased length, abnormal
co18Tg; co19Tg + MO4-tp53 chemical treatment by environment: U0126 Day 4 oligodendrocyte myelin sheath length, normal
Full text @ J. Neurosci.