FIGURE

Fig. 7

ID

ZDB-FIG-170321-29

Publication

Liu et al., 2017 - Stat3/Cdc25a-dependent cell proliferation promotes embryonic axis extension during zebrafish gastrulation

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Fig. 7

Cell number reduction correlates with axis extension defects in stat3 mutant embryos.

(A-D) Confocal image of dorsal mesoderm expressing mGFP in WT (A), Mstat3 (B), MZstat3 (C) embryos, and MZstat3 embryos overexpressing Stat3-F (D) at 11 hpf (anterior to the top). Somite boundaries are outlined in green. Adaxial cells are outlined in orange. Green arrows show AP dimension of each somite. Adaxial cells and notochord cells aligning along the AP axis are numbered in yellow. (E-G) Quantification of the average somite AP dimension (E), number of notochord cells (F) and number of adaxial cells (G) between adjacent furrows of the first two somites. (H-K) Schema of AP extension of the notochord and presomitic mesoderm. st, somite; nt, notochord. **p<0.01, ****p<0.0001, error bars = SEM.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	stat3^stl27/stl27 stat3^stl27
Observed In:	notochord cell somite adaxial cell somite anterior-posterior axis somite 1 lateral region somite 2 lateral region
Stage:	1-4 somites

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Genet.