FIGURE

Fig. 3

ID

ZDB-FIG-170210-3

Publication

Wang et al., 2016 - The somite-secreted factor Maeg promotes zebrafish embryonic angiogenesis

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Fig. 3

maeg loss of function results in the blood vessel morphogenesis defects in zebrafish embryos. A. Confocal imaging analysis of trunk vascular and somital morphology in WT, maeg^?/? and maeg morphants Tg(kdrl:EGFP) embryos at 30 hpf. Red and white square brackets indicate the lumen of the DA and PCV, respectively. DA, dorsal aorta; PCV, posterior cardinal vein; and DLAV, dorsal longitudinal anastomotic vessel. B. The statistics of ISV length in WT, maeg^?/? and maeg morphants. One-Way ANOVA; ***,P<0.001. C. The statistics of DA and PCV lumen size at 30 hpf. Error bars indicate stdev.

Expression Data

Gene:	EGFP
Fish:	s843Tg s843Tg + MO1-egfl6 egfl6^zf774/zf774; s843Tg
Knockdown Reagent:	MO1-egfl6
Anatomical Terms:	dorsal aorta intersegmental vessel posterior cardinal vein
Stage:	Prim-15

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	s843Tg + MO1-egfl6 egfl6^zf774/zf774; s843Tg
Knockdown Reagent:	MO1-egfl6
Observed In:	dorsal longitudinal anastomotic vessel blood vessel morphogenesis intersegmental vessel sprouting angiogenesis
Stage Range:	Prim-5 to Prim-15

Phenotype Detail

Acknowledgments

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