ZFIN ID: ZDB-FIG-170131-12
Boubakri et al., 2016 - Loss of ift122, a Retrograde IFT Complex Component, Leads to Slow, Progressive Photoreceptor Degeneration Due to Inefficient Opsin Transport. The Journal of biological chemistry   291(47):24465-24474 Full text @ J. Biol. Chem.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Antibodies:
Fish:
Anatomical Terms:
Stage Range: Day 4 to Days 7-13
PHENOTYPE:
Fish:
Observed In:
Stage Range: Day 4 to Days 7-13

Fig. 5 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
arr3a zpr-1 WIK standard conditions Day 4 retinal cone cell IHC
zpr-1 Day 5 retinal cone cell IHC
zpr-1 Days 7-13 retinal cone cell IHC
zpr-1 ift122jj263/jj263 standard conditions Day 4 retinal cone cell IHC
zpr-1 Day 5 retinal cone cell IHC
zpr-1 Days 7-13 retinal cone cell IHC
ift88 Ab2-ift88 WIK standard conditions Day 4 photoreceptor cell cilium IHC
Ab2-ift88 ift122jj263/jj263 standard conditions Day 4 photoreceptor cell ciliary tip IHC
Antibody Labeling Details
Antibody Assay Fish Conditions Stage Anatomy
Ab1-opn1lw IHC WIK standard conditions Day 4 photoreceptor cell photoreceptor outer segment
IHC Day 5 photoreceptor cell photoreceptor outer segment
IHC Days 7-13 photoreceptor cell cell body
IHC ift122jj263/jj263 standard conditions Day 4 photoreceptor cell cell body
IHC Day 5 photoreceptor cell cell body
IHC Day 5 photoreceptor cell photoreceptor outer segment
IHC Days 7-13 photoreceptor cell cell body
Phenotype Details
Fish Conditions Stage Phenotype
ift122jj263/jj263 standard conditions Day 4 opsin transport disrupted, abnormal
Day 4 photoreceptor cell cell body Ab1-opn1lw labeling mislocalised, abnormal
Day 4 photoreceptor cell ciliary tip ift88 expression increased amount, abnormal
Day 5 opsin transport disrupted, abnormal
Day 5 photoreceptor cell cell body Ab1-opn1lw labeling mislocalised, abnormal
Days 7-13 opsin transport disrupted, abnormal
Days 7-13 photoreceptor cell cell body Ab1-opn1lw labeling mislocalised, abnormal
Days 7-13 photoreceptor cell cell body decreased size, abnormal
Days 7-13 photoreceptor cell cilium decreased length, abnormal
Days 7-13 photoreceptor cell degenerate, abnormal
Full text @ J. Biol. Chem.