Gene

arr3a

ID

ZDB-GENE-040718-102

Name

arrestin 3a, retinal (X-arrestin)

Symbol

arr3a Nomenclature History

Previous Names

arr3l (1)
c-arrestin (1)
zgc:92697 (1)

Type

protein_coding_gene

Location

Chr: 10 Mapping Details/Browsers

Description

Predicted to have G protein-coupled receptor binding activity. Involved in visual perception. Human ortholog(s) of this gene implicated in myopia. Is expressed in epiphysis and retina. Orthologous to human ARR3 (arrestin 3).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

26 figures from 15 publications

Cross-Species Comparison

High Throughput Data

GEO (1)

Expression Atlas

UO scRNA-seq (UCSC browser)

Single Cell Expression Atlas

Daniocell

Thisse Expression Data

MGC:92697 (15 images)

Wild Type Expression Summary

Phenotype

All Phenotype Data: 1 Figure from Renninger et al., 2011
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With arr3a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
		Myopia 26, X-linked, female-limited	301010

Associated With arr3a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR017864	Arrestin, conserved site
Domain	IPR011021	Arrestin-like, N-terminal
Domain	IPR011022	Arrestin C-terminal-like domain
Family	IPR000698	Arrestin
Homologous_superfamily	IPR014752	Arrestin-like, C-terminal
Homologous_superfamily	IPR014753	Arrestin, N-terminal
Homologous_superfamily	IPR014756	Immunoglobulin E-set