Gene

arr3a

ID
ZDB-GENE-040718-102
Name
arrestin 3a, retinal (X-arrestin)
Symbol
arr3a Nomenclature History
Previous Names
  • arr3l (1)
  • c-arrestin (1)
  • zgc:92697 (1)
Type
protein_coding_gene
Location
Chr: 10 Mapping Details/Browsers
Description
Predicted to enable G protein-coupled receptor binding activity. Acts upstream of or within visual perception. Is expressed in epiphysis and retina. Human ortholog(s) of this gene implicated in myopia. Orthologous to human ARR3 (arrestin 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
21 figures from 13 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
1 Figure from Renninger et al., 2011
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With arr3a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Myopia 26, X-linked, female-limited 301010
Associated With arr3a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR017864 Arrestin, conserved site
Domain IPR011021 Arrestin-like, N-terminal
Domain IPR011022 Arrestin C-terminal-like domain
Family IPR000698 Arrestin
Family IPR033042 Arrestin-C
Homologous_superfamily IPR014752 Arrestin, C-terminal
Homologous_superfamily IPR014753 Arrestin, N-terminal
Homologous_superfamily IPR014756 Immunoglobulin E-set
Domain Details Per Protein
Protein Length Arrestin Arrestin-C Arrestin, conserved site Arrestin, C-terminal Arrestin C-terminal-like domain Arrestin-like, N-terminal Arrestin, N-terminal Immunoglobulin E-set
UniProtKB:Q49HM7 305
UniProtKB:A0A2R8RI04 344
UniProtKB:Q6DH07 357
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-arr3a Rabbit
  • IHC
  • WB
2
zpr-1 monoclonal IgG1 , k Mouse
  • IHC
Abcam plc
Zebrafish International Resource Center (ZIRC)  (order this)
308
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations