FIGURE

Fig. S10

ID

ZDB-FIG-161202-23

Publication

Bernut et al., 2016 - Mycobacterium abscessus-Induced Granuloma Formation Is Strictly Dependent on TNF Signaling and Neutrophil Trafficking

Other Figures

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Fig. S10

Distribution and mobilization of neutrophils in tnfr1 morphants.

(A) Representative bright-field and fluorescence overlay image of WT versus tnfr morphants Tg(mpx:eGFP) embryos at 2 dpf. Scale bars, 200 μm. (B) Quantification of basal number of neutrophils in whole (left) or detailed in the head, in the trunk and tail (right) of 2 dpf embryos (n = 12). Graphs represent the mean ± SEM. (C and D) Mean number of recruited neutrophils into the otic cavity in response to mock, fMLP (C) or IL8 (D) injection in WT and tnfr morphants Tg(mpx:eGFP) embryos monitored at 3 hpi. Each symbol represents an individual embryo and horizontal lines indicate the mean values. Significance was assessed by one-tailed unpaired Student’s t test comparing both embryos per category (B) or by ANOVA with Tukey post-test (C and D). (B-D) Results are representative of two independent experiments.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ PLoS Pathog.