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ZFIN ID: ZDB-FIG-161027-23
Dranow et al., 2016 - Bmp15 Is an Oocyte-Produced Signal Required for Maintenance of the Adult Female Sexual Phenotype in Zebrafish. PLoS Genetics   12:e1006323 Full text @ PLoS Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Terms:
Stage Range: Days 14-20 to Days 30-44
PHENOTYPE:
Fish:
Observed In:
Stage Range: Days 14-20 to Days 30-44

Fig. 4

(A-H′) cyp19a1a heterozygous (A, C, D, F, G) and mutant (B, E, H) gonads at 15 (A-B′), 25 (C-E′), and 35 (F-H′) dpf. Wild-type presumptive ovary (C) and ovary (F). Wild-type presumptive testis (D) and testis (G). Mutant presumptive testis (E) and testis (H). (A-H) Merged images: ziwi:EGFP in green, DNA in blue. (A′-H′) DNA only. Arrows indicate degrading germ cells. IA, stage IA oocyte; IB, stage IB oocyte; Sz, spermatozoa Scale bars: 20 µm (A-E), 50 µm (F -H′).

Gene Expression Details
Gene Antibody Fish Conditions Stage Qualifier Anatomy Assay
EGFP cyp19a1auc38/+ ; uc02Tg standard conditions Days 14-20 immature gonad IHC
Days 21-29 gonad IHC
Days 21-29 ovary IHC
Days 21-29 Not Detected testis IHC
Days 30-44 gonad IHC
Days 30-44 oocyte IHC
cyp19a1auc43/+ ; uc02Tg standard conditions Days 14-20 immature gonad IHC
Days 21-29 gonad IHC
Days 21-29 ovary IHC
Days 21-29 Not Detected testis IHC
Days 30-44 gonad IHC
Days 30-44 oocyte IHC
cyp19a1auc43/uc43 ; uc02Tg standard conditions Days 14-20 immature gonad IHC
Days 21-29 gonad IHC
Days 21-29 ovary IHC
Days 21-29 Not Detected testis IHC
Days 30-44 gonad IHC
Days 30-44 oocyte IHC
uc02Tg ; cyp19a1auc38/uc38 standard conditions Days 14-20 immature gonad IHC
Days 21-29 gonad IHC
Days 21-29 ovary IHC
Days 21-29 Not Detected testis IHC
Days 30-44 gonad IHC
Days 30-44 oocyte IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
cyp19a1auc43/uc43 ; uc02Tg standard conditions Days 14-20 germ line cell apoptotic process increased occurrence, abnormal
Days 21-29 oocyte apoptotic process premature, abnormal
Days 30-44 male gamete generation premature, abnormal
Days 30-44 oocyte apoptotic process premature, abnormal
uc02Tg ; cyp19a1auc38/uc38 standard conditions Days 14-20 germ line cell apoptotic process increased occurrence, abnormal
Days 21-29 oocyte apoptotic process premature, abnormal
Days 30-44 male gamete generation premature, abnormal
Days 30-44 oocyte apoptotic process premature, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS Genetics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Genet.