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ZFIN ID: ZDB-FIG-161027-21
Dranow et al., 2016 - Bmp15 Is an Oocyte-Produced Signal Required for Maintenance of the Adult Female Sexual Phenotype in Zebrafish. PLoS Genetics   12:e1006323 Full text @ PLoS Genet.
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Gene:
Fish:
Anatomical Term:
Stage: Days 45-89
PHENOTYPE:
Fish:
Observed In:
Stage: Days 45-89

Fig. 2

(A-F) ziwi:EGFP expression in gonads of bmp15+/- and bmp15-/- females at 80 dpf. (A) Representative bmp15+/- ovary with stage IB, stage II, and stage III oocytes indicated. (B-F) Representative regions of a single bmp15-/- gonad depicting stage IB and stage II oocytes (B), evidence of oocyte degradation and loss (C), spermatogonia surrounding a single stage IB oocyte (D), and a region containing all stages of spermatogenesis (E), including mature sperm (magnified in F). ziwi:EGFP in green, DNA in blue. Arrows indicate degrading oocytes and asterisks indicate empty follicles. Sg, spermatogonia; Sc, spermatocytes; Sz, spermatozoa. Scale bars: 50 µm (A-E), 20 µm (F).

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP bmp15uc31/uc31 ; uc02Tg standard conditions Days 45-89 oocyte IHC
uc02Tg ; bmp15uc31/+ standard conditions Days 45-89 oocyte IHC
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
bmp15uc31/uc31 ; uc02Tg standard conditions Days 45-89 female organism has extra parts of type sperm, abnormal
Days 45-89 female organism has extra parts of type spermatocyte, abnormal
Days 45-89 female organism has extra parts of type spermatogonium, abnormal
Days 45-89 female organism male gamete generation increased occurrence, abnormal
Days 45-89 female organism male, abnormal
Days 45-89 female sex determination decreased process quality, abnormal
Days 45-89 oocyte decreased amount, abnormal
Days 45-89 oocyte degeneration, abnormal
Acknowledgments:
ZFIN wishes to thank the journal PLoS Genetics for permission to reproduce figures from this article. Please note that this material may be protected by copyright. Full text @ PLoS Genet.