FIGURE

Fig. 2

ID

ZDB-FIG-160914-34

Publication

Saito et al., 2016 - Establishment of a drug evaluation model against light-induced retinal degeneration using adult pigmented zebrafish

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Fig. 2

Intravitreal administration of NAC protects against light-induced retinal degeneration in a concentration-dependent manner. (A) Typical images immunostained for zpr1 (red) and Hoechst 33342 (blue). (B-C) Quantification of ONL thickness and ONL cell number using the immunostaining results. Data are shown as means ± SEM (n = 4-6). **p < 0.01 and *p < 0.05 vs. control (Student′s t-test). ?p < 0.01 and ?p < 0.05 vs. vehicle (Dunnett test). Scale bar = 30 µm. GCL, ganglion cell layer; INL, inner nuclear layer; NAC, N-acetylcysteine; ONL, outer nuclear layer.

Expression Data

Antibody:	zpr-1
Fish:	WT
Conditions:	constant light chemical treatment by injection: N-acetyl-L-cysteine, constant light
Anatomical Term:	retinal cone cell
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Conditions:	constant light chemical treatment by injection: N-acetyl-L-cysteine, constant light
Observed In:	retinal outer nuclear layer retinal outer nuclear layer photoreceptor cell
Stage:	Adult

Phenotype Detail

Acknowledgments

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