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Fig. 2
Intravitreal administration of NAC protects against light-induced retinal degeneration in a concentration-dependent manner. (A) Typical images immunostained for zpr1 (red) and Hoechst 33342 (blue). (B-C) Quantification of ONL thickness and ONL cell number using the immunostaining results. Data are shown as means ± SEM (n = 4-6). **p < 0.01 and *p < 0.05 vs. control (Student′s t-test). ‡p < 0.01 and †p < 0.05 vs. vehicle (Dunnett test). Scale bar = 30 µm. GCL, ganglion cell layer; INL, inner nuclear layer; NAC, N-acetylcysteine; ONL, outer nuclear layer.
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