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ZFIN ID: ZDB-FIG-160829-2
Ear et al., 2015 - RAP-011 improves erythropoiesis in zebrafish model of Diamond-Blackfan anemia through antagonizing lefty1. Blood   126(7):880-90 Full text @ Blood
ADDITIONAL FIGURES
EXPRESSION / LABELING:
Genes:
Fish:
Knockdown Reagent:
Anatomical Terms:
Stage Range: 1-4 somites to Long-pec
PHENOTYPE:
Fish:
Knockdown Reagent:
Observed In:
Stage Range: 20-25 somites to Protruding-mouth

Fig. 2 ZFIN is incorporating published figure images and captions as part of an ongoing project. Figures from some publications have not yet been curated, or are not available for display because of copyright restrictions.

Gene Expression Details
Gene Antibody Fish Conditions Stage Anatomy Assay
EGFP cz3325Tg standard conditions 20-25 somites erythroid lineage cell IFL
Prim-5 erythroid lineage cell IFL
Long-pec erythroid lineage cell IFL
cz3325Tg + MO1-rpl11 standard conditions 20-25 somites erythroid lineage cell IFL
Prim-5 erythroid lineage cell IFL
Long-pec erythroid lineage cell IFL
gata1a WT standard conditions 1-4 somites erythroid lineage cell ISH
Prim-15 erythroid lineage cell ISH
WT + MO1-rpl11 standard conditions 1-4 somites erythroid lineage cell ISH
Prim-15 erythroid lineage cell ISH
pcna WT standard conditions Prim-5 intermediate cell mass of mesoderm ISH
Prim-5 whole organism ISH
WT + MO1-rpl11 standard conditions Prim-5 intermediate cell mass of mesoderm ISH
Prim-5 whole organism ISH
Antibody Labeling Details No data available
Phenotype Details
Fish Conditions Stage Phenotype
WT + MO1-rpl11 standard conditions Prim-5 intermediate cell mass of mesoderm pcna expression decreased amount, abnormal
Prim-5 intermediate cell mass of mesoderm cell population proliferation decreased occurrence, abnormal
Long-pec nucleate erythrocyte increased size, abnormal
Long-pec nucleate erythrocyte irregularly shaped, abnormal
Protruding-mouth nucleate erythrocyte increased size, abnormal
Protruding-mouth nucleate erythrocyte irregularly shaped, abnormal
cz3325Tg + MO1-rpl11 standard conditions 20-25 somites erythroid lineage cell EGFP expression decreased amount, abnormal
Prim-5 erythroid lineage cell EGFP expression decreased amount, abnormal
Long-pec erythroid lineage cell EGFP expression decreased amount, abnormal
Long-pec erythroid lineage cell increased size, abnormal
Full text @ Blood