FIGURE
Fig. S3
- ID
- ZDB-FIG-160519-8
- Publication
- Zhang et al., 2016 - A Founder Mutation in VPS11 Causes an Autosomal Recessive Leukoencephalopathy Linked to Autophagic Defects
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Fig. S3
Significant cell death in the CNS of zebrafish vps11(plt) mutants.Activated Caspase-3 was performed on cryosectioned CNS tissue from vps11(plt) mutants and wild-type siblings at 7 days post-fertilization (dpf). A) Wild-type hindbrain shows minimal apoptotic cells (arrow). B) Many apoptotic cells were observed in the vps11(plt) mutants. C) Quantification of the average number of Caspase-3+ cells observed in the hindbrain of vps11(plt) mutants and wild-type siblings at 7 dpf. Asterisk indicates significantly different from control. |
Expression Data
Expression Detail
Antibody Labeling
Phenotype Data
| Fish: | |
|---|---|
| Observed In: | |
| Stage: | Days 7-13 |
Phenotype Detail
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