FIGURE

Fig. S1

ID

ZDB-FIG-160428-26

Publication

Jimenez et al., 2016 - Phenotypic chemical screening using zebrafish neural crest reporters identifies retinoid acid as an inhibitor of epithelial morphogenesis

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Fig. S1

Expression of Tg(snai1b:GFP) During NC Development. Lateral views of (A) snail1b mRNA in situ hybridization compared to (B) GFP expression in Tg(snai1b:GFP) showing GFP-positive cells in cranial NC at 14 hpf (arrow). (C) By 18 hpf, GFP expression can be seen in the notochord (arrowhead) and within a subset of cranial NC streams (arrow). (D) Confocal maximal projection (4 µm) of dorsal view of hindbrain region in Tg(snai1b:GFP) embryos at 15 hpf processed for whole mount in situ hybridization of snail1b mRNA (red, D′) and immunofluorescence of GFP protein (green, D). Arrows highlight examples of co-localization between snail1b mRNA and GFP-positive cells in D′′. Cells expressing the highest leves of GFP (asterisk) apear mesenchymal and express decreased levels of snail1b mRNA.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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