FIGURE

Fig. 3

ID

ZDB-FIG-160428-21

Publication

Jimenez et al., 2016 - Phenotypic chemical screening using zebrafish neural crest reporters identifies retinoid acid as an inhibitor of epithelial morphogenesis

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Fig. 3

Dorsal midline neural epithelial progenitor cells display novel delamination behaviors of EMT. Schematic illustrating imaging area (top) and novel delamination behavior of a dorsal midline neuroepithelial progenitor (left); the schematic is derived from confocal time-lapse images of Tg(snai1b:GFP); Tg(sox10:RFP) embryos (right). Images show a GFP-positive cell initially spanning the dorsal midline before contracting apical attachments from each side of the neuroepithelium. Subsequently, GFP-positive cells detach and become rounded with filopodia and blebbing protrusions, and ultimately express sox10-mRFP at cell membranes. See also Movie 3.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

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