FIGURE

Fig. 1

ID

ZDB-FIG-160427-2

Publication

Ahuja et al., 2016 - Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development

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Fig. 1

id4 expression analysis in zebrafish embryos and adult hearts. (A; A′) id4 is expressed in the brain and heart at 52 hpf. In the heart, expression is enriched in the AVC (red arrow) and inflow tract (black arrow). (B) Lack of id4 expression in clo mutant hearts suggests that id4 is expressed in the endocardium. (C; C′) In the adult heart, id4 is expressed in the atrium (black arrow) and AV canal (red arrow) exclusively. myh6 (atrial mhc) was used as a positive control for the atrium. (D) qPCR analysis of id4 expression in the adult zebrafish heart. (E) Section through adult heart after whole mount in situ hybridization. Arrows point to endocardial expression of id4 in the adult atrium and AVC. Scale bars, 100 µm. A, atrium; AVC, atrioventricular canal; V, ventricle.

Expression Data

Genes:	id4 myh6
Fish:	AB npas4l^s5/s5
Anatomical Terms:	atrioventricular canal atrium brain endocardium heart
Stage Range:	Long-pec to Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	npas4l^s5/s5
Observed In:	endocardium heart
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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Reprinted from Developmental Biology, 412(1), Ahuja, S., Dogra, D., Stainier, D.Y., Reischauer, S., Id4 functions downstream of Bmp signaling to restrict TCF function in endocardial cells during atrioventricular valve development, 71-82, Copyright (2016) with permission from Elsevier. Full text @ Dev. Biol.