ZFIN ID: ZDB-GENE-051113-208
Gene Name: inhibitor of DNA binding 4
Gene Symbol: id4    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: Id4 (1), cb547 (1), fb77d04, sb:cb547, wu:fb77d04, zgc:123214 (1)

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 16 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II transcription factor binding activity. Involved in atrioventricular canal development; atrioventricular valve development; and regulation of Wnt signaling pathway involved in heart development. Predicted to colocalize with the cytoplasm. Is expressed in central nervous system; heart; and retina. Orthologous to human ID4 (inhibitor of DNA binding 4, HLH protein).
Genome Resources: Alliance (1),  Gene:664761 (1),  Ensembl(GRCz11):ENSDARG00000045131 (2)
GENE EXPRESSION
All Expression Data: 15 figures from 6 publications
Directly Submitted Expression Data: 5 figures (16 images) from Thisse et al., 2001 [cb547]
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Adult (90d-730d, breeding adult)
 
Curated Microarray Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns18 Small Deletion Exon 1 Frameshift TALEN
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
TALEN1-id4 1
DISEASE ASSOCIATED WITH id4 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH id4 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process atrioventricular canal development (more)
Cellular Component cytoplasm (more)
Molecular Function protein dimerization activity (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
Type InterPro ID Name
Domain IPR011598 Myc-type, basic helix-loop-helix (bHLH) domain
Family IPR026052 DNA-binding protein inhibitor
Homologous_superfamily IPR036638 Helix-loop-helix DNA-binding domain superfamily
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA id4-201 (1)    Ensembl 1191
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM id4
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(cryaa:EGFP,hsp70l:id4) cryaahsp70l EGFPid4 Danio rerio 1 3
MARKER RELATIONSHIPS
id4 Contained in: [BAC] CH211-179P9 (1)
id4 Encodes: [EST] cb547 (1) (order this), fb77d04
[cDNA] MGC:123214 (1)
SEQUENCE INFORMATION
Type Accession # Length (bp/aa) Analysis
RNA RefSeq:NM_001039990 (1) 1174 bp
Genomic GenBank:CR388383 (1) 145770 bp
Select Tool
Polypeptide UniProtKB:Q32PN8 (1) 126 aa
Sequence Information (all 16)
ORTHOLOGY for id4 ( Chr: 16 )
CITATIONS (29)