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Fig. 2

ID

ZDB-FIG-160205-85

Publication

Marsden et al., 2015 - In�Vivo Ca(2+) Imaging Reveals that Decreased Dendritic Excitability Drives Startle Habituation

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Fig. 2

Graded M-Cell Lateral Dendrite Ca²⁺ Signals Reflect Startle Probability

(A) Increasing stimulus intensity increases activity at the M-cell lateral dendrite (white dashed line), with no change in somatic (blue dashed line) activity unless a startle is performed (scale bar, 10�m).

(B) Representative ΔF/F₀ traces from a single M-cell show graded lateral dendrite responses. Stimuli were calibrated with an accelerometer, with voltage outputs converted to dB using the formula dB = 20 log (V/0.775).

(C) Grouped ΔF/F₀ data reveal all-or-none somatic activity (blue bars) in startles versus non-startles regardless of stimulus intensity and graded lateral dendrite activity (white bars; p < 0.05, p < 0.001, p < 0.0001, one-way ANOVA with Dunnett?s multiple comparison test). Error bars indicate SEM.

(D) Scatterplot of peak lateral dendrite ΔF/F₀ with startle events in red and no startle events in white. Gray bar indicates the lateral dendrite activation threshold for startle behavior.

Expression Data

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Antibody Labeling

Phenotype Data

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Acknowledgments

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