FIGURE

Fig. 1

ID

ZDB-FIG-160205-117

Publication

Bhadra et al., 2015 - Hsp47 mediates Cx43-dependent skeletal growth and patterning in the regenerating fin

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Fig. 1

serpinh1b is differentially expressed in wild-type, sof ^b123 and alf ^dty86. Whole mount in situ hybridization shows increased expression in alf ^dty86 (C) and decreased expression in sof ^b123 (B) compared to wild-type (A). In situ hybridization on cryosection of a WT-5 dpa fin (D) reveals localization of serpinh1b in the blastema (b), basal layer of epidermis (ble) and skeletal precursor cells (*). Epidermis is denoted by ‘e’, mesenchyme by ‘m’, lepidotrichia by ‘l’ and actinotrichia by ‘a’. The amputation plane is indicated in panels A and B. The amputation plane is beyond the field of view in C. The scale bars in C and D are 50µm; the scale bar in C applies to the images in A, B, and C.

Expression Data

Gene:	serpinh1b
Fish:	WT gja1b^b123/b123 kcnk5b^ty86d/ty86d
Condition:	amputation: fin
Anatomical Terms:	basal regeneration epithelium blastema regenerating fin regenerating fin mesenchyme
Stage:	Adult

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	gja1b^b123/b123 kcnk5b^ty86d/ty86d
Condition:	amputation: fin
Observed In:	regenerating fin
Stage:	Adult

Phenotype Detail

Acknowledgments

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Reprinted from Mechanisms of Development, 138 Pt 3, Bhadra, J., Iovine, M.K., Hsp47 mediates Cx43-dependent skeletal growth and patterning in the regenerating fin, 364-74, Copyright (2015) with permission from Elsevier. Full text @ Mech. Dev.