FIGURE

Fig. 2

ID

ZDB-FIG-151125-32

Publication

Boyd et al., 2015 - Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness

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Fig. 2

Expression of disc1 at 50hpf is up-regulated around the midline of the hindbrain in response to increased Shh signalling. Expression was analysed using whole mount in situ hybridization. Dorsal, anterior to left (A,C) and transverse sectional (B,D) views show increased disc1 expression around the midline of the hindbrain in ptch1;ptch2 mutants (C,D) compared with siblings (A,B). Arrows indicate hindbrain midline disc1 expression in transverse sectional views.

Expression Data

Gene:	disc1
Fish:	WT ptch1^tj222/+; ptch2^{hu1602/hu1602}
Anatomical Terms:	diencephalon ventral region hindbrain axial region hindbrain dorso-lateral region
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	ptch1^tj222/+; ptch2^{hu1602/hu1602}
Observed In:	hindbrain axial region
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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