FIGURE

Fig. 5

ID

ZDB-FIG-151125-34

Publication

Boyd et al., 2015 - Sonic hedgehog functions upstream of disrupted-in-schizophrenia 1 (disc1): implications for mental illness

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Fig. 5

Cyclopamine treatment leads to a dramatic reduction in the number of olig2-positive cells specified in the hindbrain. Cyclopamine (50µm) was applied to wild type embryos from 32hpf then embryos analysed for olig2 expression at 52hpf. Cyclopamine-treated embryos (B) show a greatly reduced number of olig2-positive cells (arrow) compared with 0.5% ethanol treated (A) and untreated (C) control embryos. n=40, 20 embryos per group, data pooled from 2 independent experiments.

Expression Data

Gene:	olig2
Fish:	WT
Condition:	chemical treatment: Cyclopamine
Anatomical Term:	hindbrain glioblast (sensu Vertebrata)
Stage:	Long-pec

Expression Detail

Antibody Labeling

Phenotype Data

Fish:	WT
Condition:	chemical treatment: Cyclopamine
Observed In:	hindbrain glioblast (sensu Vertebrata)
Stage:	Long-pec

Phenotype Detail

Acknowledgments

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