FIGURE

Fig. S7

ID

ZDB-FIG-151103-16

Publication

Bednarek et al., 2015 - Telomerase Is Essential for Zebrafish Heart Regeneration

Other Figures

All Figure Page

Back to All Figure Page

Fig. S7

Cardiac cells with accumulated DNA damage are less prone to proliferate.

(A) Immunofluorescence staining on a WT and a tert^-/- heart section with anti-BrdU (red) and anti-γH2AX (green). Nuclei are counterstained with DAPI (blue). (A1-A4) Boxed areas in the whole-mount heart views of WT (A1,A2) and tert^-/- (A3,A4) are shown at high magnification in the right panels to exemplify individual BrDU-positive cells. Scale bars: 100 µm (whole mount views), 10 µm (magnifications).

(B) Quantification of cells double positive for BrDU and γH2AX. Data are means ± SEM of 4 sections/heart from a total of 3 hearts per condition (p=0.106, unpaired Student’s t-test). ns, not significant.

Related to Figure 6.

Expression Data

Expression Detail

Antibody Labeling

Phenotype Data

Phenotype Detail

Acknowledgments

This image is the copyrighted work of the attributed author or publisher, and ZFIN has permission only to display this image to its users. Additional permissions should be obtained from the applicable author or publisher of the image. Full text @ Cell Rep.